Donate PPE -Medical Physics Webinar(2): Sublethal repair effects in SRS - by Ian Paddick

Until recently, the effects of sublethal repair during treatment have been ignored by the radiosurgery community. There is now a growing body of evidence to suggest that repair during prolonged treatment times has a significant clinical effect. The biologically effective dose is a convenient way of predicting the overall clinical effect of the physical prescription dose modulated by the treatment delivery time. A simplified method of calculating the BED will be explained, and tools for prescribing iso-BED treatments will be shared, allowing the user to compensate for delivery time by adjusting the physical prescription dose.